Qin Xu Selected Research

Prodrugs

1/2023	A co-delivery system based on chlorin e6-loaded ROS-sensitive polymeric prodrug with self-amplified drug release to enhance the efficacy of combination therapy for breast tumor cells.
1/2022	IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy.
12/2020	Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy.
10/2020	Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.
1/2017	Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature.

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Qin Xu Research Topics

Disease

90	Neoplasms (Cancer) 05/2024 - 04/2000
27	Stroke (Strokes) 03/2024 - 08/2006
23	Neoplasm Metastasis (Metastasis) 10/2023 - 06/2003
21	Ischemic Stroke 03/2024 - 08/2006
20	Squamous Cell Carcinoma of Head and Neck 01/2021 - 11/2003
19	Inflammation (Inflammations) 03/2024 - 03/2006
19	Malaria 12/2023 - 01/2016
18	Alzheimer Disease (Alzheimer's Disease) 11/2024 - 09/2003
15	Transient Ischemic Attack 03/2024 - 09/2021
13	Cardiovascular Diseases (Cardiovascular Disease) 05/2024 - 04/2005
13	Leiomyoma (Uterine Fibroids) 09/2011 - 02/2005
11	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2024 - 08/2017
10	Mouth Neoplasms (Oral Cancer) 01/2024 - 04/2004
10	Infections 03/2022 - 04/2004
9	Hemorrhage 03/2024 - 11/2006
9	Carcinoma (Carcinomatosis) 06/2023 - 04/2000
9	Falciparum Malaria (Plasmodium falciparum Malaria) 03/2023 - 12/2015
8	COVID-19 01/2023 - 10/2020
8	Breast Neoplasms (Breast Cancer) 01/2023 - 10/2014
7	Stomach Neoplasms (Stomach Cancer) 02/2024 - 06/2021
7	Frailty 02/2024 - 01/2023
7	Fibrosis (Cirrhosis) 01/2024 - 04/2008
7	Carcinogenesis 09/2023 - 08/2010
7	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022 - 08/2010
6	Body Weight (Weight, Body) 09/2022 - 06/2002
5	Obesity 10/2023 - 01/2016
5	Weight Loss (Weight Reduction) 10/2023 - 04/2017
4	Lymphatic Metastasis 11/2023 - 08/2010
4	Hypertension (High Blood Pressure) 08/2023 - 02/2019
4	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 01/2017
3	Pain (Aches) 01/2024 - 01/2022

Drug/Important Bio-Agent (IBA)

51	Proteins (Proteins, Gene)FDA Link 01/2024 - 04/2004
19	artemisinin (artemisinine)IBA 11/2023 - 12/2015
17	Biomarkers (Surrogate Marker)IBA 01/2024 - 06/2002
12	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 03/2014
12	Apolipoprotein E4IBA 05/2024 - 09/2003
12	DNA (Deoxyribonucleic Acid)IBA 02/2024 - 04/2000
12	RNA (Ribonucleic Acid)IBA 01/2024 - 08/2019
11	Messenger RNA (mRNA)IBA 11/2022 - 09/2004
10	piperaquineIBA 04/2023 - 11/2018
10	Progesterone Receptors (Progesterone Receptor)IBA 11/2010 - 02/2005
9	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 03/2024 - 01/2023
9	TicagrelorIBA 03/2024 - 01/2023
9	EnzymesIBA 01/2024 - 04/2008
9	Indicators and Reagents (Reagents)IBA 12/2023 - 04/2004
8	Clopidogrel (Plavix)FDA Link 03/2024 - 01/2023
7	Long Noncoding RNAIBA 01/2024 - 08/2019
7	Metalloproteases (Metalloproteinases)IBA 01/2018 - 03/2008
7	ulipristalIBA 09/2011 - 02/2005
7	ApolipoproteinsIBA 03/2011 - 09/2003
6	Triglycerides (Triacylglycerol)IBA 02/2024 - 06/2010
6	Cytochrome P-450 CYP2C19IBA 02/2024 - 01/2023
6	Peptides (Polypeptides)IBA 01/2023 - 04/2004
6	NF-kappa B (NF-kB)IBA 01/2023 - 09/2009
6	TrichosanthinIBA 12/2022 - 01/2017
6	Matrix Metalloproteinases (MMPs)IBA 09/2022 - 03/2008
6	Liposomes (Liposome)IBA 04/2022 - 01/2017
6	CytokinesIBA 03/2022 - 12/2018
6	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 05/2004
6	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 01/2013
6	asoprisnilIBA 09/2011 - 04/2006
6	Progesterone FDA LinkGeneric 11/2010 - 04/2006
5	oxidized low density lipoproteinIBA 03/2024 - 06/2010
5	Hemoglobins (Hemoglobin)IBA 01/2024 - 08/2017
5	Phosphotransferases (Kinase)IBA 09/2023 - 07/2013
5	VaccinesIBA 01/2023 - 01/2020
5	ProdrugsIBA 01/2023 - 01/2017
5	CollagenIBA 11/2022 - 03/2008
5	MicroRNAs (MicroRNA)IBA 06/2021 - 03/2013
5	Proliferating Cell Nuclear Antigen (PCNA)IBA 11/2010 - 04/2000
4	LipopolysaccharidesIBA 01/2024 - 03/2018
4	TabletsIBA 11/2023 - 12/2019
4	Glutathione (Reduced Glutathione)IBA 10/2023 - 01/2022
4	LipidsIBA 01/2023 - 03/2009
4	Uric Acid (Urate)IBA 01/2023 - 01/2023
4	Competitive Endogenous RNAIBA 01/2022 - 01/2020
4	Transcription Factors (Transcription Factor)IBA 12/2021 - 08/2018
4	Complement System Proteins (Complement)IBA 01/2021 - 03/2006
4	LigandsIBA 01/2021 - 02/2007
4	ORALIT (ORS)IBA 01/2021 - 01/2014
4	HMGB1 Protein (HMG1)IBA 12/2019 - 08/2018
4	DisintegrinsIBA 01/2018 - 06/2010
4	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 08/2014 - 03/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2010 - 09/2006
4	Teniposide (VM 26)FDA Link 06/2005 - 11/2002
3	B7-H1 AntigenIBA 05/2024 - 01/2022
3	PlatinumIBA 05/2024 - 01/2022
3	C-Reactive ProteinIBA 03/2024 - 04/2005
3	Alanine Transaminase (SGPT)IBA 03/2024 - 01/2021
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 02/2024 - 01/2017
3	GoldIBA 01/2024 - 01/2020

Therapy/Procedure

64	Therapeutics 03/2024 - 07/2006
19	Drug Therapy (Chemotherapy) 05/2024 - 05/2004
11	Immunotherapy 01/2023 - 04/2004
7	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 09/2009
6	Length of Stay 08/2023 - 07/2019
4	Gastrectomy 02/2024 - 01/2021
4	Mass Drug Administration 04/2023 - 11/2018
4	Lasers (Laser) 01/2021 - 08/2006
3	Neoadjuvant Therapy 04/2024 - 01/2011